Revised defined daily doses
Posted in News
As noted in the January Newsletter the new and revised list of ATC codes and DDDs (Defined Daily Doses) released by the World Health Organization (WHO) was not updated at the end of 2018 following feedback from Trusts. The update was released on the 29th of April and all of the new and amended ATC codes and DDDs have been applied to your data.
Those working in antimicrobial stewardship are reminded that the DDD for several commonly used antibiotics has been increased. As Define® and Refine® calculate DDDs actively this will affect all data within the system both prior to and after the change and will result in an apparent decrease in the number of DDDs used for these items – but with no effect on the underlying values. A good start for reporting in antimicrobials is the total consumption per 1,000 admissions report, available here.
The changes are for antimicrobial products are:
| ATC Code | ATC Name | Previous DDD | New DDD | Route |
| J01CA01 | ampicillin | 2g | 6g | Parenteral |
| J01CA04 | amoxicillin | 1g | 1.5g | Oral |
| J01CA04 | amoxicillin | 1g | 3g | Parenteral |
| J01CA17 | temocillin | 2g | 4g | Parenteral |
| J01CR02 | amoxicillin and beta lactamase inhibitor | 1g | 1.5g | Oral |
| J01DE01 | cefepime | 2g | 4g | Parenteral |
| J01DH02 | meropenem | 2g | 3g | Parenteral |
| J01MA02 | ciprofloxacin | 0.5g | 0.8g | Parenteral |
| J01XB01 | colistin | 3 Mega Units | 9 Mega Units | Parenteral |